The Pineal Gland: "Introduction
The Pineal Gland (epiphysis cerebri in mammals), conferred as "the seat of Human soul" by Rene Descartes in 17th century,
was considered as an epithalamic appendage of the vertebrate brain, and a vestigial evolutionary element until the 19th century.
http://www.photobiology.info/Tosini.html
The endocrine aspect of the pineal gland reported in the early 20th century was confirmed through isolation of the hormone melatonin by Aaron B. Lerner in 1958.
The pineal thus attracted scientific attention in the late 20th century due to its crucial role of transducing photoperiodic information through the rhythmic secretion of the daily and annual timekeeping hormone melatonin."
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